Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28012829 | 1.00 | KDM1A (0.81) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL23719208 | 0.90 | KDM1A (1.00) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL19283326 | 0.90 | KDM1A (1.00) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL14712657 | 0.90 | KDM1A (1.00) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL684658 | 0.89 | KDM1A (0.83) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL684476 | 0.88 | KDM1A (0.81) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL685110 | 0.87 | KDM1A (0.75) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL684817 | 0.87 | KDM1A (0.79) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL684487 | 0.87 | KDM1A (0.79) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL684473 | 0.86 | MTOR (0.77) | KDM1ANPC1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006136008-A1 | SALICYLIC ACID HYDRAZONES AS INHIBITORS OF THE ERK MAPKINASE PATHWAY AND FOR THE TREATMENT OF CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2006-12-28 | — | — | WO | claimed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| WO-2006136008-A1 | SALICYLIC ACID HYDRAZONES AS INHIBITORS OF THE ERK MAPKINASE PATHWAY AND FOR THE TREATMENT OF CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | KDM1A 484/4885NPC1 1690/4885SMN1; SMN2 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.