SCHEMBL6851767

SCHEMBL6851767

CC=CC(=O)C(=O)CC[Si](C)(OC)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911076 0.83
SCHEMBL10705114 0.79 TSHR (0.31)
SCHEMBL1305971 0.74 POLB (0.35)
SCHEMBL18419469 0.71 ALDH1A1 (0.39)
SCHEMBL6861922 0.70 ATM (0.38)
SCHEMBL27826252 0.69
SCHEMBL2166992 0.69
SCHEMBL3208067 0.69 CES1 (0.52)
SCHEMBL3503930 0.69 TSHR (0.39)
SCHEMBL865267 0.68 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6780934-B2 POLYETHERSILOXANE COPOLYMER; SEALS, COATINGS, ADHESIVES ASAHI GLASS COMPANY LTD. (JP) 2004-08-24 US disclosed
EP-1396513-A1 Room temperature-setting composition Asahi Glass Company, Limited (JP) 2004-03-10 EP disclosed
EP-0918062-B1 ROOM TEMPERATURE SETTING COMPOSITIONS ASAHI GLASS CO LTD (JP) 2004-02-18 EP disclosed
US-20030092863-A1 Room temperature-setting composition ASAHI GLASS COMPANY LIMITED (JP) 2003-05-15 US disclosed
US-6207766-B1 A ROOM TEMPERATURE SETTING POLYOXYALKYLENE OXIDE POLYMER CONTAINING HYDROLYZABLE SILICON GROUPS AT THE TERMINAL; HAVING AN EXCELLENT CURING PROPERTY AND BEING CAPABLE OF SHOWING AN ADEQUATE STRENGTH PROPERTY IN A SHORT TIME ASAHI GLASS COMPANY LTD. (JP) 2001-03-27 US disclosed
EP-0918062-A1 ROOM TEMPERATURE SETTING COMPOSITIONS Asahi Glass Company Ltd. (JP) 1999-05-26 EP disclosed