SCHEMBL10705114

SCHEMBL10705114

C=CC(=O)C(=O)CC[Si](C)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8155361 0.85 ALDH1A1 (0.32) TSHR
SCHEMBL8153459 0.82
SCHEMBL6851767 0.79
SCHEMBL18419469 0.76 ALDH1A1 (0.39) TSHR
SCHEMBL1305038 0.73 ALDH1A1 (0.37) TSHR
SCHEMBL865267 0.73 ALDH1A1 (0.37) TSHR
SCHEMBL18059876 0.72 HPGD (0.30) TSHR
Acrylic Acid SCHEMBL28765921 0.71 LMNA (0.40) TSHR
SCHEMBL3503930 0.70 TSHR (0.39) TSHR
SCHEMBL733859 0.69 TSHR (0.50) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3070133-B1 TIMEPIECE OR PIECE OF JEWELLERY COMPRISING A SURFACE COVERED WITH AN EPILAME AGENT AND METHOD FOR EPILAMING SUCH A SUBSTRATE SWATCH GROUP RES & DEV LTD (CH) 2019-02-20 EP disclosed
EP-3070152-B1 SUBSTRATE COMPRISING A SURFACE COVERED WITH AN EPILAMIZATION AGENT AND METHOD FOR EPILAMING SUCH A SUBSTRATE SWATCH GROUP RES & DEV LTD (CH) 2018-02-28 EP disclosed
EP-3070152-A1 SUBSTRATE COMPRISING A SURFACE COVERED WITH AN EPILAMIZATION AGENT AND METHOD FOR EPILAMING SUCH A SUBSTRATE The Swatch Group Research and Development Ltd. (CH) 2016-09-21 EP disclosed
EP-3070133-A1 SUBSTRATE COMPRISING A SURFACE COVERED WITH AN EPILAME AGENT AND METHOD FOR EPILAMING SUCH A SUBSTRATE The Swatch Group Research and Development Ltd. (CH) 2016-09-21 EP disclosed
EP-0293733-A2 Process for producing a curable polymer composition Kanegafuchi Chemical Industry Co., Ltd. (JP) 1988-12-07 EP disclosed