Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 6/20 | 0.68 |
| ▸ | MMP1 | P03956 | 15/20 | 0.63 |
| ▸ | MMP3 | P08254 | 10/20 | 0.63 |
| ▸ | MMP2 | P08253 | 8/20 | 0.63 |
| ▸ | MMP7 | P09237 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | MMP8 | P22894 | 7/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851738 | 0.93 | MMP1 (0.66) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL6852364 | 0.90 | FCER2 (0.81) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL7406329 | 0.86 | MMP1 (0.80) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL6851903 | 0.81 | FCER2 (1.00) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL6852647 | 0.81 | FCER2 (0.77) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL19360818 | 0.80 | MMP1 (0.60) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL22652874 | 0.78 | MMP1 (0.68) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL6851741 | 0.78 | FCER2 (0.80) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL6851850 | 0.78 | FCER2 (0.61) | FCER2MMP1MMP3MMP2MMP7 | |
| SCHEMBL15505966 | 0.77 | MMP1 (1.00) | FCER2MMP1MMP3MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011181-A1 | PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AMICUS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |