Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.66 |
| ▸ | MMP3 | P08254 | 12/20 | 0.66 |
| ▸ | MMP2 | P08253 | 9/20 | 0.66 |
| ▸ | MMP7 | P09237 | 5/20 | 0.66 |
| ▸ | FCER2 | P06734 | 5/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 5/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851874 | 0.93 | FCER2 (0.68) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL6852364 | 0.88 | FCER2 (0.81) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL7406329 | 0.84 | MMP1 (0.80) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL9288857 | 0.80 | MMP3 (1.00) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL6851903 | 0.79 | FCER2 (1.00) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL6852647 | 0.79 | FCER2 (0.77) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL8777266 | 0.78 | MMP2 (0.81) | MMP1MMP3MMP2MMP7MMP9 | |
| SCHEMBL30035567 | 0.77 | MMP1 (1.00) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL3503805 | 0.77 | MMP1 (0.76) | MMP1MMP3MMP2MMP7FCER2 | |
| SCHEMBL13253276 | 0.77 | MMP1 (0.76) | MMP1MMP3MMP2MMP7FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011181-A1 | PHARMACOLOGICAL CHAPERONES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | AMICUS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |