Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853770 | 0.87 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAHTTTSHR | |
| SCHEMBL9999689 | 0.85 | MAPT (0.51) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL114725 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL29473917 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL20309118 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL20032264 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL17996505 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| Methane SCHEMBL28862287 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL188108 | 0.81 | UGT2B7 (0.56) | ALDH1A1SMN1; SMN2LMNANPC1POLB | |
| SCHEMBL30745165 | 0.81 | UGT2B7 (0.56) | ALDH1A1SMN1; SMN2LMNANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |