Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | OGA | O60502 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852153 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACASP1HTT | |
| SCHEMBL20032281 | 0.83 | CYP3A4 (0.58) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL12386875 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL17541507 | 0.81 | UGT2B7 (0.56) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL30644683 | 0.81 | UGT2B7 (0.56) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL3611078 | 0.80 | LMNA (0.44) | ALDH1A1MEN1KMT2AOGALMNA | |
| SCHEMBL14587149 | 0.79 | CYP3A4 (0.43) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL903412 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL24312390 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL24869977 | 0.77 | CYP3A4 (0.55) | ALDH1A1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |