SCHEMBL6852405

SCHEMBL6852405

C1=CC(c2cccs2)c2cccc3cccc1c23

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C19 P33261 1/20 0.42
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29455223 0.83 SLC6A2 (0.36) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL7722775 0.83 SLC6A2 (0.36) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL28884018 0.77 KDM4E (0.30) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL27895796 0.75 ALDH1A1 (0.30) ALDH1A1HPGDCYP1A2
SCHEMBL3470484 0.75 MEN1 (0.37) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL21994346 0.73 KDM1A (0.40) ALDH1A1MAPTHPGDKDM4EALOX12
SCHEMBL28437775 0.72 MEN1 (0.42) MEN1ALDH1A1KMT2ASLC6A2SLC6A4
SCHEMBL2466948 0.72
SCHEMBL10356785 0.72
SCHEMBL28806765 0.72 ALDH1A1 (0.34) MEN1ALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1342169-A Oxocyclobutazone-one derivatives JOHN JASON GENTRY MULLINS (US) 2002-03-27 CN claimed
CN-104995706-A Photoelectric conversion element and solar cell comprising same KONICA MINOLTA INC 2015-10-21 CN disclosed
CN-1852934-B Conjugated polymers, their preparation and use thereof MERCK PATENT GMBH (DE) 2011-12-21 CN disclosed
CN-101235135-B Aromatic polycarbonate, electrophotographic photoreceptor, and image forming apparatus SHARP KK 2011-11-02 CN disclosed
CN-101235135-A Aromatic polycarbonate, electrophotographic photoreceptor, and image forming apparatus SHARP KK (JP) 2008-08-06 CN disclosed
CN-100379796-C Dendritic polymer and electronic device element using the same SHARP KK (JP) 2008-04-09 CN disclosed
CN-1873545-A Asymmetric bis-hydroxyenamine compound, electrophotographic photoreceptor and image forming apparatus SHARP KK (JP) 2006-12-06 CN disclosed
CN-1852934-A Conjugated polymers, their preparation and use thereof MERCK OLED MATERIALS GMBH (DE) 2006-10-25 CN disclosed
CN-1774464-A Dendrimer and electronic device element using the same SHARP KK (JP) 2006-05-17 CN disclosed
US-6699621-B2 ELECTROPOLYMERIZING MONOMERS ON TO A SUBSTRATE IN A POLYMERIZATION SOLUTION; ELECTROCHEMICALLY CONDITIONING POLYMER SO AS TO INCREASE DISCHARGE EFFICIENCY AND CHARGE CAPACITY; DOPING TO IMPART A NON-NEUTRAL CHARGE JOHNS HOPKINS UNIVERSITY 2004-03-02 US disclosed
US-20030143461-A1 METHOD FOR ELECTROCHEMICAL CONDITIONING POLYMERIC ELECTRODEDS JOHNS HOPKINS UNIVERSITY 2003-07-31 US disclosed
CN-1342169-A Oxocyclobutazone-one derivatives JOHN JASON GENTRY MULLINS (US) 2002-03-27 CN disclosed
WO-2000041255-A1 METHOD FOR ELECTROCHEMICAL CONDITIONING POLYMERIC ELECTRODES JOHNS HOPKINS UNIVERSITY (US) 2000-07-13 WO disclosed