Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025256 | 0.87 | KDM1A (0.43) | KDM1AALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL28231919 | 0.85 | ERBB2 (0.35) | ALDH1A1HPGDHSD17B10CYP1A2KDM4E | |
| SCHEMBL21326205 | 0.83 | L3MBTL1 (0.36) | ALDH1A1HPGDHSD17B10CYP1A2KDM4E | |
| SCHEMBL28438624 | 0.82 | GPR3 (0.36) | ALDH1A1HPGDHSD17B10CYP1A2MAPT | |
| SCHEMBL28806765 | 0.81 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10L3MBTL1CYP2A6 | |
| SCHEMBL2466948 | 0.81 | — | — | |
| SCHEMBL20472624 | 0.81 | CYP1A2 (0.41) | ALDH1A1HPGDHSD17B10CYP1A2L3MBTL1 | |
| SCHEMBL3470484 | 0.81 | MEN1 (0.37) | ALDH1A1HPGDHSD17B10CYP1A2MAPT | |
| SCHEMBL28445320 | 0.79 | KIF11 (0.43) | ALDH1A1HPGDHSD17B10CYP1A2KDM4E | |
| SCHEMBL27893873 | 0.79 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3887479-A1 | ELECTRONIC DEVICE | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-3887378-A1 | ELECTRONIC DEVICE | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| WO-2020109269-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |