⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169460 | 0.84 | — | — | |
| SCHEMBL4507262 | 0.84 | LMNA (0.35) | — | |
| SCHEMBL1317309 | 0.84 | MGAM (0.39) | — | |
| SCHEMBL14873850 | 0.82 | — | — | |
| SCHEMBL20169456 | 0.80 | — | — | |
| SCHEMBL8723542 | 0.80 | — | — | |
| SCHEMBL7502361 | 0.80 | — | — | |
| SCHEMBL15457915 | 0.80 | — | — | |
| SCHEMBL26171282 | 0.80 | — | — | |
| SCHEMBL20169458 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692771-A1 | POLYOXYETHYLENE DERIVATIVE HAVING A PLURALITY OF HYDROXYL GROUPS AT END | NOF Corporation (JP) | 2014-02-05 | — | — | EP | disclosed |
| EP-2319854-A1 | Bioconjugation Of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2319855-A1 | Bioconjugation of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2256133-A1 | Bioconjugation of macromolecules | Sigma-Aldrich Co. (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-1029867-B1 | Process for the preparation of organic azides | AKZO NOBEL NV (NL) | 2004-04-28 | — | — | EP | disclosed |