Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852455 | 0.84 | — | — | |
| SCHEMBL12809790 | 0.84 | LMNA (0.48) | LMNAL3MBTL1TDP1MGAMKDM4E | |
| SCHEMBL29023787 | 0.84 | LMNA (0.48) | LMNAL3MBTL1TDP1MGAMKDM4E | |
| SCHEMBL1682659 | 0.81 | — | — | |
| SCHEMBL3797668 | 0.81 | — | — | |
| SCHEMBL811246 | 0.81 | — | — | |
| SCHEMBL20169446 | 0.81 | MGAM (0.37) | LMNAL3MBTL1TDP1MGAM | |
| SCHEMBL1317309 | 0.80 | MGAM (0.39) | TDP1MGAM | |
| SCHEMBL8433347 | 0.79 | LMNA (0.35) | LMNAL3MBTL1MGAM | |
| SCHEMBL10038815 | 0.79 | MGAM (0.30) | MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023223186-A1 | ADHESION MODIFIER COMPOSITION, AND CURABLE COMPOSITION AND METHOD OF BONDING INCLUDING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| US-20170198099-A1 | COMPOSITION CONTAINING PLATINUM | EVONIK DEGUSSA GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
| EP-2900064-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | Zoetis LLC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20150111884-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | ZOETIS SERVICES LLC | 2015-04-23 | — | — | US | disclosed |
| US-8952149-B2 | Tricyclic tetrahydroquinoline antibacterial agents | ZOETIS LLC (US) | 2015-02-10 | — | — | US | disclosed |
| US-20140088093-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | ZOETIS LLC (US) | 2014-03-27 | — | — | US | disclosed |
| EP-2620439-A1 | 8-pyrazinyl-S-spiropyrimidinetrione-oxazinoquinoline derivatives as antibacterial agents | PAH USA 15 LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| US-20090275536-A1 | Antibacterial Agents | PFIZER INC | 2009-11-05 | — | — | US | disclosed |
| US-7557100-B2 | Antibacterial agents | PFIZER INC. (US) | 2009-07-07 | — | — | US | disclosed |
| EP-1971612-A1 | 8-PYRAZINYL-S-SPIROPYRIMIDINETRIONE-OXAZINOQUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Pfizer Products Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20070197518-A1 | Antibacterial agents | WARNER LAMBERT COMPANY LLC | 2007-08-23 | — | — | US | disclosed |
| WO-2007072151-A1 | 8-PYRAZINYL-S-SPIROPYRIMIDINETRIONE-OXAZINOQUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275536-A1 | Antibacterial Agents | CLPP, MRPL21, SPOUT1 | LMNA 2171/4885L3MBTL1 2857/4885TDP1 3679/4885 |
| US-20070197518-A1 | Antibacterial agents | CLPP, MRPL21, SPOUT1 | LMNA 2171/4885L3MBTL1 2857/4885TDP1 3679/4885 |
| US-20150111884-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | TOP1, SDHA, TOP2A | LMNA 2185/4885L3MBTL1 4038/4885TDP1 2460/4885 |
| US-20140088093-A1 | TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS | TOP1, TOP2A, AAAS | LMNA 1784/4885L3MBTL1 3153/4885TDP1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.