Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852508 | 1.00 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL6852503 | 1.00 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL6853977 | 0.82 | RAB9A (0.36) | CYP19A1 | |
| SCHEMBL6853988 | 0.82 | RAB9A (0.36) | CYP19A1 | |
| SCHEMBL6853982 | 0.82 | RAB9A (0.36) | CYP19A1 | |
| SCHEMBL6852359 | 0.82 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL6852349 | 0.82 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL6850524 | 0.79 | QDPR (0.37) | CYP19A1 | |
| SCHEMBL6850522 | 0.79 | QDPR (0.37) | CYP19A1 | |
| SCHEMBL6850514 | 0.79 | QDPR (0.37) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |