Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 2/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 2/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 1/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | THPO | P40225 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | NPY1R | P25929 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | NPY2R | P49146 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852543 | 1.00 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10684309 | 0.94 | ADORA3 (0.89) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10684302 | 0.94 | ADORA3 (0.89) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10686730 | 0.94 | ADORA3 (0.89) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10686723 | 0.94 | ADORA3 (0.89) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10685562 | 0.93 | ADORA3 (0.86) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL10683942 | 0.93 | ADORA2A (0.86) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL10683936 | 0.93 | ADORA2A (0.86) | ADORA3ADORA2AADORA1ADORA2BTSHR | |
| SCHEMBL10685557 | 0.93 | ADORA3 (0.86) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 | |
| SCHEMBL4754960 | 0.92 | ADORA3 (0.86) | ADORA3ADORA2AADORA1ADORA2BSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996453-B1 | METHODS FOR THE INHIBITION OF NEURONAL ACTIVITY BY LOCAL DELIVERY OF ADENOSINE | MOHLER HANNS (CH) | 2004-04-28 | — | — | EP | claimed |
| EP-0139358-B1 | N6-SUBSTITUTED DIARYLALKYL ADENOSINES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | WARNER-LAMBERT COMPANY (US) | 1988-11-09 | — | — | EP | claimed |
| EP-0251339-A2 | N6- substituted diarylalkyl adenosines, processes for their production and pharmaceutical compositions comprising the same | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |