Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722198 | 0.85 | PDPK1 (0.77) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL5967788 | 0.83 | PDPK1 (0.63) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL21791658 | 0.83 | LOXL2 (0.71) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL534382 | 0.80 | LOXL2 (1.00) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL533558 | 0.80 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL28842595 | 0.80 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL1439923 | 0.80 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL533419 | 0.80 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6HDAC2 | |
| SCHEMBL8240124 | 0.80 | LOXL2 (0.67) | LOXL2ADRB2PDPK1CYP2A6ABL1 | |
| Hydrochloric Acid SCHEMBL533729 | 0.78 | LOXL2 (0.96) | LOXL2ADRB2PDPK1CYP2A6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20040106607-A1 | New compounds | ASTRAZENECA AB AND NPS PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106607-A1 | New compounds | MTX1, MLX, TPX2 | LOXL2 3388/4885ADRB2 402/4885PDPK1 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.