Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Triphenyl Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenyl Phosphate SCHEMBL3825293 | 1.00 | SRC (0.61) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| Triphenyl Phosphate SCHEMBL9622348 | 0.93 | SRC (0.70) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| Triphenyl Phosphate SCHEMBL7202263 | 0.93 | SRC (0.70) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| Triphenyl Phosphate SCHEMBL27831754 | 0.93 | SRC (0.56) | SRCTDP1L3MBTL1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL4454667 | 0.92 | SRC (0.57) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL2137987 | 0.89 | CYP3A4 (0.52) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL360818 | 0.89 | CYP3A4 (0.52) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| Biphenyl SCHEMBL27663828 | 0.87 | SRC (0.61) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL473247 | 0.86 | CYP3A4 (0.54) | SRCTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL431694 | 0.86 | CYP3A4 (0.54) | SRCTDP1L3MBTL1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020213389-A1 | THERMOPLASTIC RESIN, MOLDED OBJECT, AND MONOMER FOR THERMOPLASTIC RESIN | 三菱瓦斯化学株式会社 | 2020-10-22 | — | — | WO | disclosed |
| WO-2020189409-A1 | POLYESTER CARBONATE RESIN, AND MOLDED BODY WHICH IS OBTAINED BY MOLDING RESIN COMPOSITION CONTAINING SAID RESIN | 三菱瓦斯化学株式会社 | 2020-09-24 | — | — | WO | disclosed |
| WO-2014031530-A1 | INHIBITING CORROSION CAUSED BY AQUEOUS ALDEHYDE SOLUTIONS | BAKER HUGHES INCORPORATED (US) | 2014-02-27 | — | — | WO | disclosed |
| US-20130224092-A1 | INHIBITING CORROSION CAUSED BY AQUEOUS ALDEHYDE SOLUTIONS | BAKER HUGHES INCORPORATED (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130090271-A1 | INHIBITING CORROSION CAUSED BY AQUEOUS ALDEHYDE SOLUTIONS | BAKER HUGHES INCORPORATED (US) | 2013-04-11 | — | — | US | disclosed |
| US-6764540-B2 | THE DYE IS DISSOLVED OR DISPERSED IN AN AQUEOUS MEDIUM CONTAINING A COMPOUND CAPABLE OF INCLUDING A DYE, SUCH AS A ROTAXANE MOLECULE OR A MOLECULAR NANOTUBE | FUJI PHOTO FILM CO., LTD. (JP) | 2004-07-20 | — | — | US | disclosed |
| US-20030061965-A1 | Ink compositions and ink jet recording method | FUJIFILM CORPORATION (JP) | 2003-04-03 | — | — | US | disclosed |