Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Triphenyl Phosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphenyl Phosphate SCHEMBL9622348 | 1.00 | SRC (0.70) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL3825293 | 0.93 | SRC (0.61) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL6852665 | 0.93 | SRC (0.61) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL28761613 | 0.92 | SRC (0.64) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL18116 | 0.92 | SRC (0.64) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL28557783 | 0.92 | SRC (0.64) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL483692 | 0.92 | SRC (0.64) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL6852668 | 0.91 | SRC (0.64) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| Triphenyl Phosphate SCHEMBL2530073 | 0.90 | SRC (0.61) | SRCL3MBTL1TDP1CYP3A4TSHR | |
| SCHEMBL10015245 | 0.90 | CYP3A4 (0.61) | SRCL3MBTL1TDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6322882-B1 | CONTAINING A PHOSPHORIC ESTER AND A DISPERSED SUBSTANCE CONTAINING A POLYSILOXANE AND SILICA HAVING AN ASPECT RATIO OF NOT LESS THAN ABOUT 2; SUPERIOR HEAT RESISTANCE AND FLAME RESISTANCE WITHOUT USE OF ANY HALOGEN-CONTAINING MATERIALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-27 | — | — | US | claimed |
| JP-5201161-A | — | — | None | — | — | JP | disclosed |
| WO-2023080158-A1 | POLYIMIDE PRECURSOR COMPOSITION, AND PRODUCTION METHOD THEREFOR | ＵＢＥ株式会社 | 2023-05-11 | — | — | WO | disclosed |
| EP-3810674-A1 | PROCESS FOR PRODUCING POLYOL | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-04-28 | — | — | EP | disclosed |
| EP-2921520-B1 | FLAME-RETARDANT FOAMED STYRENE RESIN COMPOSITION | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 2020-02-05 | — | — | EP | disclosed |
| WO-2019243435-A1 | PROCESS FOR PRODUCING POLYOL | COVESTRO DEUTSCHLAND AG (DE) | 2019-12-26 | — | — | WO | disclosed |
| CN-108481913-B | Printing ink absorbing means, ink-jet printer | 精工爱普生株式会社 | 2019-12-03 | — | — | CN | disclosed |
| CN-110320753-A | Photosensitive polymer combination | 株式会社田村制作所 | 2019-10-11 | — | — | CN | disclosed |
| CN-108481913-A | Printing ink absorbing means, ink-jet printer | 精工爱普生株式会社 | 2018-09-04 | — | — | CN | disclosed |
| CN-103895354-B | Liquid absorber, liquid absorption tank, and electronic device | 精工爱普生株式会社 | 2018-07-24 | — | — | CN | disclosed |
| CN-1715331-A | Method for producing sheet transport roll, urethane composition used therefor, and sheet transport roll obtained thereby | TOKAI RUBBER IND LTD (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1665854-A | Vinyl chloride copolymer resin for paste, composition, and process for producing | KANEGAFUCHI CHEMICAL IND (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1142961-C | Polyesters including isosorbide as a comonomer and methods for making same | 纳幕尔杜邦公司 | 2004-03-24 | — | — | CN | disclosed |
| EP-0970997-B1 | Flame retardant polycarbonate/abs composition | CHEIL IND INC (KR) | 2003-11-12 | — | — | EP | disclosed |
| CN-1112991-C | Isosorbide containing polyesters and methods for making same | DU PONT (US) | 2003-07-02 | — | — | CN | disclosed |
| CN-1298416-A | Polyesters including isosorbide as a comonomer and methods for making same | DU PONT (US) | 2001-06-06 | — | — | CN | disclosed |
| CN-1298343-A | Isosorbide containing polyesters and methods for making same | DU PONT (US) | 2001-06-06 | — | — | CN | disclosed |
| EP-0970997-A2 | Flame retardant polycarbonate/abs composition | Cheil Industries Inc. (KR) | 2000-01-12 | — | — | EP | disclosed |
| JP-H05201161-A | DYE THERMAL-TRANSFER IMAGE RECEIVING SHEET | OJI PAPER CO LTD | 1993-08-10 | — | — | JP | disclosed |
| US-5053155-A | a mixture of tetrafluoroethanes and polyoxyproplene glycol lu bricants automobiles | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-01 | — | — | US | disclosed |