Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176036 | 0.80 | P2RX7 (0.45) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL6176040 | 0.80 | P2RX7 (0.45) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL1189963 | 0.80 | P2RX7 (0.46) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL1008150 | 0.80 | P2RX7 (0.46) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL3333497 | 0.80 | P2RX7 (0.46) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL1008151 | 0.80 | P2RX7 (0.46) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL29135687 | 0.78 | EHMT2 (0.45) | EHMT2HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL29135683 | 0.78 | EHMT2 (0.45) | EHMT2HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL10215486 | 0.78 | P2RX7 (0.47) | P2RX7EHMT2HCRTR1HCRTR2MEN1 | |
| SCHEMBL6133023 | 0.78 | P2RX7 (0.45) | P2RX7EHMT2HCRTR1HCRTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023733-A1 | ANHYDRATE FORMS OF A PYRIDINE DERIVATIVE | GLAXOSMITHKLINE LLC (US) | 2011-03-03 | — | — | WO | disclosed |