Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.59 |
| ▸ | F3 | P13726 | 2/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163064 | 1.00 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL7160152 | 0.88 | GSR (0.50) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL7160153 | 0.88 | GSR (0.50) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL6023839 | 0.85 | PKM (0.55) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL6023835 | 0.85 | PKM (0.55) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL8490792 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL8490788 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL6853027 | 0.76 | TTR (0.44) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL6848726 | 0.76 | TTR (0.44) | CYP1A2CYP2C9CYP2D6CYP3A4CYP2B6 | |
| SCHEMBL2390177 | 0.75 | CYP3A4 (0.64) | CYP3A4ALOX5TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541672-B1 | Showing anti-bacterial, antioxidant, and anti-inflammatory activities that enable them to be used for drugs | FACULTY OF PHARMACY, THE UNIVERSITY OF GADJAH MADA (ID) | 2003-04-01 | — | — | US | claimed |
| EP-0860422-A1 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone and their synthesis. | The University of Gajah Mada (ID) | 1998-08-26 | — | — | EP | claimed |
| US-6777447-B2 | ANTIINFLAMMATORY AGENTS, BACTERICIDES, OXIDATION RESISTANCE, ANTICANCER AGENTS | GADJAH MADA, FACULTY OF PHARMACY, UNIVERSITY OF, THE (ID) | 2004-08-17 | — | — | US | disclosed |
| US-20030092772-A1 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof | GADJAH MADA, FACULTY OF PHARMACY, UNIVERSITY OF, THE (ID) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092772-A1 | Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof | GSTK1, GSTP1, CAT | CYP1A2 258/4885CYP2C9 346/4885CYP2D6 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.