Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533842 | 0.89 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| Hydrochloric Acid SCHEMBL23859924 | 0.89 | ADORA2A (0.71) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| SCHEMBL940189 | 0.86 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| SCHEMBL1081737 | 0.77 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| Hydrochloric Acid SCHEMBL6754869 | 0.76 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| SCHEMBL2295172 | 0.76 | ADORA2A (0.65) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| SCHEMBL6852905 | 0.76 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| Hydrochloric Acid SCHEMBL9247444 | 0.76 | ADORA2A (0.70) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| Hydrochloric Acid SCHEMBL2031971 | 0.76 | ADORA2A (0.67) | ADORA2AADORA3ADORA1ADORA2BALOX15 | |
| SCHEMBL724837 | 0.75 | ADORA2A (0.58) | ADORA2AADORA3ADORA1ADORA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996453-B1 | METHODS FOR THE INHIBITION OF NEURONAL ACTIVITY BY LOCAL DELIVERY OF ADENOSINE | MOHLER HANNS (CH) | 2004-04-28 | — | — | EP | claimed |