SCHEMBL6853050

SCHEMBL6853050

c1cc(-c2ccc3ccc4cccc5ccc2c3c45)c(-c2ccc3ccc4cccc5ccc2c3c45)c(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
IKBKB O14920 1/20 0.32
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6852814 0.85 HPRT1 (0.39) PDK2ALDH1A1HPGDTSHRHSD17B10
SCHEMBL3855053 0.75 ALDH1A1 (0.48) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL27945675 0.74 ALDH1A1 (0.41) PDK2ALDH1A1CYP3A4HPGDTSHR
SCHEMBL29814212 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL2124728 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL29413360 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL5334139 0.68 ALDH1A1 (0.56) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL3043614 0.68 SLC6A3 (0.41) ALDH1A1HTT
SCHEMBL25125225 0.67 PTPN11 (0.34) ALDH1A1CYP3A4HPGDHSD17B10HTT
Phosphine SCHEMBL28240146 0.66 SLC6A3 (0.41) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6777111-B1 HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE KABUSHIKI KAISHA CHUO KENKYUSHO (JP) 2004-08-17 US disclosed