SCHEMBL6853102

SCHEMBL6853102

c1cc2ccc3ccc(C4C5CC6CC(C5)CC4(c4ccc5ccc7cccc8ccc4c5c78)C6)c4ccc(c1)c2c34

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ERBB2 P04626 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30855592 0.84 CYP1A2 (0.36) ALDH1A1HPGDHSD17B10ERBB2CYP1A2
SCHEMBL30855587 0.74 ERBB2 (0.35) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL30855591 0.69
SCHEMBL30855593 0.69
SCHEMBL30855589 0.68
SCHEMBL6853054 0.67 CYP1A2 (0.33) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL30978073 0.64 MAPT (0.37) ALDH1A1HPGDTSHRHSD17B10
SCHEMBL1269355 0.64 MAPT (0.37) ALDH1A1HPGDTSHRHSD17B10
SCHEMBL7125342 0.64 HSD11B1 (0.30)
SCHEMBL11546535 0.64 HTR2C (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6777111-B1 HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE KABUSHIKI KAISHA CHUO KENKYUSHO (JP) 2004-08-17 US disclosed