SCHEMBL7125342

SCHEMBL7125342

Brc1cccc(C2C3CC4CC(C3)CC2(c2cccc(Br)c2Br)C4)c1Br

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.30
HSD11B2 P80365 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28877624 0.73 ALDH1A1 (0.37) HSD11B1
SCHEMBL1269355 0.72 MAPT (0.37) HSD11B1HSD11B2
SCHEMBL30978073 0.72 MAPT (0.37) HSD11B1HSD11B2
SCHEMBL30855591 0.71
SCHEMBL11546535 0.71 HTR2C (0.36) HSD11B1HSD11B2
SCHEMBL30855589 0.69
SCHEMBL29092411 0.69
SCHEMBL6364298 0.68
SCHEMBL6766442 0.68
SCHEMBL22494195 0.67 KDM1A (0.42) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030143332-A1 Coating solution for forming insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030143332-A1 Coating solution for forming insulating film TET1, TAS1R1, ITGA1 HSD11B1 2971/4885HSD11B2 3904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.