Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.32 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.32 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408090 | 0.76 | PDE7A (0.48) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL8471852 | 0.76 | PDE7A (0.48) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL6853483 | 0.76 | PDE7A (0.48) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL21940203 | 0.72 | PDE7A (0.50) | PDE7AAKR1B1IDO1AKR1A1PGR | |
| SCHEMBL1722012 | 0.64 | PGR (0.69) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL5380796 | 0.63 | AKR1B1 (0.53) | PDE7AAKR1B1AKR1A1LMNA | |
| SCHEMBL9539072 | 0.62 | PDE7A (0.57) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL9539797 | 0.61 | PDE7A (0.46) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL19260231 | 0.61 | AHR (0.54) | PDE7AAKR1B1IDO1MEN1KMT2A | |
| SCHEMBL2480561 | 0.61 | AKR1B1 (0.68) | PDE7AAKR1B1IDO1AKR1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745785-B1 | Pharmaceutical composition for preventing or treating cerebral oedema | BIOCODEX (FR) | 2011-03-09 | — | — | EP | disclosed |