Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19166978 | 0.88 | ALDH1A1 (0.45) | PDE10AKDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL1458362 | 0.86 | RIPK2 (0.41) | KDM4EALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL16220978 | 0.86 | ALDH1A1 (0.40) | PDE10AKDM4EALDH1A1TDP1NR4A3 | |
| SCHEMBL16212146 | 0.84 | ALDH1A1 (0.40) | PDE10AKDM4EALDH1A1TDP1NR4A3 | |
| SCHEMBL9105724 | 0.83 | CYP1A2 (0.48) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL1458251 | 0.83 | PDE10A (0.44) | PDE10AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9926248 | 0.81 | KDM4E (0.38) | PDE10AKDM4EALDH1A1TDP1NR4A3 | |
| SCHEMBL1458264 | 0.79 | CYP2C9 (0.47) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL9106126 | 0.79 | POLB (0.49) | PDE10APOLB | |
| SCHEMBL1458454 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540807-B | For the method preparing pyrazole carboxylic acid derivant | 霍夫曼-拉罗奇有限公司 | 2016-09-14 | — | — | CN | disclosed |
| EP-2885276-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2016-06-01 | — | — | EP | disclosed |
| CN-104540807-A | Process for the preparation of pyrazole carboxylic acid derivatives | HOFFMANN LA ROCHE | 2015-04-22 | — | — | CN | disclosed |
| CN-102791714-B | N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as PDE10A inhibitors | HOFFMANN LA ROCHE | 2015-03-25 | — | — | CN | disclosed |
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-8129493-B2 | Aromatic polyester | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | MURORAN INSTITUTE OF TECHNOLOGY (JP) | 2011-09-15 | — | — | US | disclosed |
| US-20110092662-A1 | AROMATIC POLYESTER | NITTA CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224343-A1 | MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME | F12, PHAX, WDR82 | PDE10A 2818/4885KDM4E 717/4885ALDH1A1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.