Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 16/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 16/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 16/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 16/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 16/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 16/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854867 | 0.85 | NPC1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6852609 | 0.81 | NPC1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL155825 | 0.77 | P2RX7 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6852506 | 0.76 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Hydrochloric Acid SCHEMBL194977 | 0.76 | P2RX7 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9224077 | 0.76 | MEN1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6920437 | 0.76 | USP30 (0.43) | CNR2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18527128 | 0.75 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL194790 | 0.74 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL194967 | 0.74 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059048-A1 | NOVEL AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2011-05-19 | — | — | WO | disclosed |