Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681921 | 0.82 | ALDH1A1 (0.34) | ALDH1A1CYP3A4 | |
| SCHEMBL8827802 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CYP3A4 | |
| SCHEMBL21378 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4APLNR | |
| SCHEMBL247292 | 0.75 | — | — | |
| SCHEMBL9642004 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4APLNR | |
| SCHEMBL174369 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4APLNR | |
| SCHEMBL19444447 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4APLNR | |
| SCHEMBL580581 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4APLNR | |
| SCHEMBL25269364 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CYP3A4 | |
| SCHEMBL15574 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338537-B2 | Surface modifying macromolecules with high degradation temperatures and uses thereof | INTERFACE BIOLOGICS INC. (CA) | 2012-12-25 | — | — | US | disclosed |
| US-20120220724-A1 | SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF | INTERFACE BIOLOGICS INC. (CA) | 2012-08-30 | — | — | US | disclosed |
| US-8178620-B2 | Surface modifying macromolecules with high degradation temperatures and uses thereof | INTERFACE BIOLOGICS INC. (CA) | 2012-05-15 | — | — | US | disclosed |
| US-20110271961-A1 | SURFACE MODIFYING MACROMOLECULES WITH HIGH DEGRADATION TEMPERATURES AND USES THEREOF | INTERFACE BIOLOGICS INC. (CA) | 2011-11-10 | — | — | US | disclosed |
| EP-0352984-B1 | Polymeric sleeve for surgical instruments | ALLERGAN INC (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0352984-A1 | Polymeric sleeve for surgical instruments | ALLERGAN, INC (US) | 1990-01-31 | — | — | EP | disclosed |
| US-4897079-A | Polymeric sleeve for surgical instruments | ALLERGAN, INC. (US) | 1990-01-30 | — | — | US | disclosed |
| US-4845180-A | POLYURETHANES FOR CONTACT LENSES AND EYEGLASSES | ALLERGAN, INC. (US) | 1989-07-04 | — | — | US | disclosed |