Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15574 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4 | |
| SCHEMBL25269364 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP3A4 | |
| SCHEMBL685381 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4 | |
| Cyclohexane SCHEMBL3386540 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CYP3A4 | |
| SCHEMBL14388538 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP3A4 | |
| SCHEMBL2808914 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD11B1 | |
| SCHEMBL174369 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4 | |
| SCHEMBL247292 | 0.76 | — | — | |
| SCHEMBL9642004 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4 | |
| SCHEMBL21378 | 0.76 | ALDH1A1 (0.72) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556366-B | Compound having mutant isocitrate dehydrogenase inhibitory activity, process for producing the same, and use thereof | 上海海和药物研究开发股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| WO-2024214806-A1 | PIGMENT DISPERSION LIQUID, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, BLACK MATRIX, AND IMAGE DISPLAY DEVICE | 三菱ケミカル株式会社 | 2024-10-17 | — | — | WO | disclosed |
| WO-2024017706-A1 | METHOD FOR PRODUCING A COMPOSITE COMPONENT WITH A SUPPORT COMPRISING POLYCARBONATE OF A SPECIFIC OH CONTENT | COVESTRO DEUTSCHLAND AG (DE) | 2024-01-25 | — | — | WO | disclosed |
| CN-105658398-A | Polycarbonate composition with improved adhesion to polyurethane layers | 科思创德国股份有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-1601306-B | Process of producing plastic lens and plastic lens | HOYA CORP | 2010-10-13 | — | — | CN | disclosed |
| CN-1601306-A | Process of producing plastic lens and plastic lens | HOYA CORP (JP) | 2005-03-30 | — | — | CN | disclosed |
| US-5663190-A | INHIBITORS OF ACETYLCHOLINESTERASE, TREATMENT OF ALZHEIMER*S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5639892-A | ANTIDEPRESSANTS, ALZHEIMER'S DISEASE | HOECHST-MARION-ROUSSEL, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5621114-A | REACTING A THIO OR PHENOL COMPOUND WITH 1,1-CARBONYLIMIDAZOLE OR 1,1-THIOCARBONYLDIIMIDAZOLE, REACTING THE INTERMEDIATE WITH SECONDARY AMINE COMPOUND; USEFUL AS ANALGESIC AND MEMORY ENHANCING AGENT | HOECHST MARION ROUSSEL, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| US-5550254-A | REACTING CARBOXYLIC ACID WITH CARBONYLDIIMIDAZOLE OR THIOCARBONYLDIIMIDAZOLE, ADDING PHENOL OR THIOPHENOL COMPOUND | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5550253-A | REACTING PHENOL OR THIOPHENOL DERIVATIVE WITH LOWER ALKYL P-TOLUENESULFONATE, OPTIONALLY REDUCING NITRO GROUPS TO AMINO GROUPS AND ACYLATING OR ALKYLATING THEM | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5547977-A | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8(and 1,3A,8)-di (and Tri) methylpyrrolo (2,3-B) indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| US-5541340-A | Method of preparing 1,2,3,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-Di(and Tri)methylpyrrolo[2,3,-b] indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5541216-A | Memory enhancing and analgsic 1,2,3,3A,8,8A-Hexahydro--3A, 8(And1,3A,8)-Di (and Tri) Methylpyrrolo(2,3-B Indoles | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-07-30 | — | — | US | disclosed |
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-4791107-A | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0253372-A2 | 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-01-20 | — | — | EP | disclosed |