Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850043 | 0.93 | ALDH1A1 (0.40) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6855682 | 0.91 | HDAC6 (0.40) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6850033 | 0.90 | TP53 (0.39) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6854071 | 0.89 | TP53 (0.41) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6853738 | 0.89 | TP53 (0.38) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6855392 | 0.89 | MAPT (0.38) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6850222 | 0.88 | MAPT (0.44) | MAPTTP53ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6854439 | 0.87 | MAPT (0.51) | MAPTTP53ALDH1A1TSHRHPGD | |
| SCHEMBL6850131 | 0.87 | LMNA (0.43) | MAPTTP53ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6849963 | 0.87 | MAPT (0.39) | MAPTTP53ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |