Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854292 | 1.00 | PIK3CD (0.36) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL6854283 | 1.00 | PIK3CD (0.36) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL27612840 | 0.82 | PIK3CD (0.38) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL6850682 | 0.78 | PIK3CD (0.37) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL6850690 | 0.78 | PIK3CD (0.37) | PIK3CDPIP5K1CPI4KAPIK3CGPI4KB | |
| SCHEMBL6879073 | 0.76 | ADRB2 (0.42) | AOC3ADRB2CLK4NPC1POLB | |
| SCHEMBL6276439 | 0.76 | ADRB2 (0.42) | AOC3ADRB2CLK4NPC1POLB | |
| SCHEMBL6309957 | 0.76 | ADRB2 (0.42) | AOC3ADRB2CLK4NPC1POLB | |
| SCHEMBL6853692 | 0.76 | CLK4 (0.39) | AOC3KAT6AADRB2CLK4DYRK1A | |
| SCHEMBL6853694 | 0.76 | CLK4 (0.39) | AOC3KAT6AADRB2CLK4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |