Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 1.00 |
| ▸ | BCHE | P06276 | 4/20 | 1.00 |
| ▸ | ACHE | P22303 | 3/20 | 0.68 |
| ▸ | CNR1 | P21554 | 8/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917500 | 0.81 | CNR2 (1.00) | CNR2BCHEACHECNR1GABRA1 | |
| SCHEMBL27800056 | 0.71 | CNR2 (0.80) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL9917511 | 0.69 | CNR2 (0.67) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL9917496 | 0.68 | CNR2 (0.65) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL9917403 | 0.67 | CNR2 (0.81) | CNR2BCHEACHECNR1GABRA1 | |
| SCHEMBL27578623 | 0.65 | CNR2 (0.70) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL516208 | 0.65 | CNR2 (0.66) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL19793130 | 0.65 | CNR2 (0.66) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL28045003 | 0.65 | CNR2 (0.68) | CNR2BCHEACHECNR1KDM4E | |
| SCHEMBL21872251 | 0.64 | CNR2 (0.48) | CNR2BCHECNR1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200281897-A1 | INDAZOLE DERIVATIVES FOR CANCER TREATMENT | SERVICIO ANDALUZ DE SALUD (ES) | 2020-09-10 | — | — | US | claimed |
| US-20200281897-A1 | INDAZOLE DERIVATIVES FOR CANCER TREATMENT | SERVICIO ANDALUZ DE SALUD (ES) | 2020-09-10 | — | — | US | disclosed |
| WO-2011039388-A2 | 3-INDAZOLYL ETHER FAMILY WITH CANNABINOID AND/OR CHOLINERGIC PROPERTIES | UNIVERSIDAD REY JUAN CARLOS (ES) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281897-A1 | INDAZOLE DERIVATIVES FOR CANCER TREATMENT | MCL1, IDH3A, IDH3B | CNR2 3591/4885BCHE 2484/4885ACHE 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.