Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859729 | 0.84 | PDK2 (0.39) | KDM4EMAPTMAPK1PDK2 | |
| SCHEMBL6854556 | 0.76 | PDK2 (0.47) | MAPTPDK2 | |
| SCHEMBL6854806 | 0.76 | PDK2 (0.47) | MAPTPDK2 | |
| SCHEMBL6854533 | 0.76 | PDK2 (0.47) | MAPTPDK2 | |
| SCHEMBL8722118 | 0.76 | KDM4E (0.47) | KDM4EELANEMAPTMAPK1PTPN1 | |
| SCHEMBL5678543 | 0.71 | KDM4E (0.46) | KDM4EELANEMAPTMAPK1 | |
| SCHEMBL686585 | 0.70 | KDM4E (0.48) | KDM4EELANEMAPTMAPK1 | |
| SCHEMBL16585654 | 0.69 | BACE1 (0.47) | KDM4EELANEMAPTMAPK1PTPN1 | |
| SCHEMBL7551541 | 0.68 | KDM4E (0.46) | KDM4EELANEMAPTMAPK1 | |
| SCHEMBL3628405 | 0.67 | KDM4E (0.42) | KDM4EELANEMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968175-B1 | SPIRO COMPOUNDS AND THE USE THEREOF | CELANESE VENTURES GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |