Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067481 | 0.88 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL23957686 | 0.69 | KMT2A (0.44) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL3462062 | 0.68 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL861501 | 0.68 | LMNA (0.61) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL31516755 | 0.68 | KDM4E (0.58) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL46317 | 0.68 | KDM4E (0.58) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL3155897 | 0.68 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL2728318 | 0.68 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL22925970 | 0.68 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL29696397 | 0.68 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |