Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450207 | 0.82 | SLC2A1 (0.83) | SLC2A1ALDH1A1TSHRCYP19A1NR1H3 | |
| SCHEMBL14384030 | 0.82 | SLC2A1 (0.83) | SLC2A1ALDH1A1TSHRCYP19A1NR1H3 | |
| SCHEMBL17942172 | 0.81 | ALDH1A1 (0.46) | SLC2A1ALDH1A1TSHRNR1H3CRHBP | |
| Hydrochloric Acid SCHEMBL29837416 | 0.80 | SLC2A1 (0.79) | SLC2A1ALDH1A1TSHRCYP19A1NR1H3 | |
| SCHEMBL10923509 | 0.80 | ALDH1A1 (0.52) | SLC2A1ALDH1A1TSHRNR1H3KMT2A | |
| SCHEMBL16284366 | 0.78 | ESR1 (0.47) | ALDH1A1TSHRNR1H3KMT2AL3MBTL1 | |
| SCHEMBL7812347 | 0.75 | ALDH1A1 (0.50) | SLC2A1ALDH1A1TSHRKMT2ACYP2D6 | |
| SCHEMBL17942209 | 0.75 | GABRA1 (0.46) | SLC2A1ALDH1A1TSHRCYP19A1NR1H3 | |
| SCHEMBL30901511 | 0.74 | TSHR (0.48) | ALDH1A1TSHRKMT2AMAPK1GAA | |
| SCHEMBL17506577 | 0.74 | CYP19A1 (0.51) | TSHRCYP19A1KMT2ACYP2D6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828159-B1 | Carbopyronine fluorescent dyes | Drexhage, Karl-Heinz (DE) | 2004-12-07 | — | — | US | disclosed |
| EP-1173519-B1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL-HEINZ (DE) | 2003-08-20 | — | — | EP | disclosed |
| EP-1173519-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE, Karl-Heinz (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064986-A1 | NOVEL CARBOPYRONINE FLUORESCENCE DYES | DREXHAGE KARL HEINZ (DE) | 2000-11-02 | — | — | WO | disclosed |