Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848304 | 0.92 | TSHR (0.56) | LMNAALDH1A1TSHREPHX2TBXAS1 | |
| SCHEMBL17520245 | 0.82 | LMNA (0.63) | LMNAALDH1A1TSHREPHX2TBXAS1 | |
| SCHEMBL5883708 | 0.80 | ALDH1A1 (0.60) | LMNAALDH1A1TSHREPHX2TBXAS1 | |
| SCHEMBL15757660 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL810916 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL6569696 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL6055455 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL1524543 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL13273157 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL | |
| SCHEMBL1524542 | 0.79 | ALDH1A1 (0.70) | LMNAALDH1A1TSHREPHX2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-4950666-A | INSECTS, ACARIDS, AND NEMATODES | FMC CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |