SCHEMBL6854928

SCHEMBL6854928

CC(C)(N)C1CCC(F)(F)CC1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
TDP1 Q9NUW8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2125652 0.79 ALDH1A1 (0.36) ALDH1A1TDP1
SCHEMBL12408519 0.77 ALDH1A1 (0.70) ALDH1A1TDP1
SCHEMBL25029022 0.75 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL22733404 0.75 TRPA1 (0.36) ALDH1A1TDP1
SCHEMBL18389197 0.75 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL2520236 0.75 ALDH1A1 (1.00) ALDH1A1TDP1
SCHEMBL242895 0.75 ALDH1A1 (1.00) ALDH1A1TDP1
SCHEMBL2520233 0.75 ALDH1A1 (1.00) ALDH1A1TDP1
SCHEMBL19079535 0.75 ALDH1A1 (0.59) ALDH1A1TDP1
SCHEMBL1231253 0.74 ALDH1A1 (0.57) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011013644-A1 SUBSTITUTED PIPERIDINE COMPOUND 第一三共株式会社 (JP) 2011-02-03 WO disclosed