Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.35 |
| ▸ | FABP7 | O15540 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856330 | 0.77 | FABP5 (0.33) | FABP5FABP7MDM4TP53 | |
| SCHEMBL6800164 | 0.77 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2DPP8 | |
| SCHEMBL6856244 | 0.77 | KMT2A (0.41) | KMT2AFABP5FABP7EPHX2DPP8 | |
| SCHEMBL6855043 | 0.74 | KMT2A (0.37) | KMT2AFABP5FABP7EPHX2DPP8 | |
| SCHEMBL14891093 | 0.73 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL29402007 | 0.73 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL30821975 | 0.73 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL2043044 | 0.73 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL6955887 | 0.72 | CHRM2 (0.42) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL16250397 | 0.69 | KMT2A (0.42) | KMT2AFABP5FABP7EPHX2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828427-B1 | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same | ISIS PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |