SCHEMBL2043044

SCHEMBL2043044

O=C(OCC1c2ccccc2-c2ccccc21)N1CCCC1CO

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
PDK2 Q15119 3/20 0.43
SPHK2 Q9NRA0 1/20 0.42
FABP7 O15540 1/20 0.41
FABP5 Q01469 1/20 0.41
CHRM3 P20309 5/20 0.41
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
CHRM1 P11229 2/20 0.41
EPHX2 P34913 1/20 0.40
F2 P00734 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA5 P30532 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30821975 1.00 L3MBTL1 (0.45) L3MBTL1POLBKMT2AMEN1PDK2
SCHEMBL14891093 1.00 L3MBTL1 (0.45) L3MBTL1POLBKMT2AMEN1PDK2
SCHEMBL29402007 1.00 L3MBTL1 (0.45) L3MBTL1POLBKMT2AMEN1PDK2
SCHEMBL6955887 0.96 CHRM2 (0.42) L3MBTL1POLBKMT2AMEN1PDK2
SCHEMBL30821987 0.89 KMT2A (0.41) KMT2AFABP7FABP5CHRM3EPHX2
SCHEMBL18148919 0.89 KMT2A (0.47) KMT2AFABP7FABP5CHRM3EPHX2
SCHEMBL10118378 0.89 NPC1 (0.45) L3MBTL1KMT2AMEN1FABP7FABP5
SCHEMBL29600664 0.89 KMT2A (0.41) KMT2AFABP7FABP5CHRM3EPHX2
SCHEMBL7096605 0.89 KMT2A (0.41) KMT2AFABP7FABP5CHRM3EPHX2
SCHEMBL6309080 0.89 KMT2A (0.41) KMT2AFABP7FABP5CHRM3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034093-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 US disclosed
US-20240358675-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2024-10-31 US disclosed
EP-3252057-B1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC (US) 2024-03-27 EP disclosed
US-20220387382-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2022-12-08 US disclosed
US-10894033-B2 Multicyclic compounds and methods of use thereof SUNOVION PHARMACEUTICALS INC. (US) 2021-01-19 US disclosed
US-20200323819-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2020-10-15 US disclosed
US-20190125722-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2019-05-02 US disclosed
US-10085968-B2 Multicyclic compounds and methods of use thereof SUNOVION PHARMACEUTICALS INC. (US) 2018-10-02 US disclosed
EP-2933333-B1 SINGLE-STRAND NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION BONAC CORP (JP) 2018-02-21 EP disclosed
EP-3252057-A2 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF Sunovion Pharmaceuticals Inc. (US) 2017-12-06 EP disclosed
EP-2431466-A1 SINGLE-STRAND NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION Bonac Corporation (JP) 2012-03-21 EP disclosed
US-20120035246-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING NITROGEN-CONTAINING ALICYCLIC SKELETON BONAC CORPORATION (JP) 2012-02-09 US disclosed
US-20120035246-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING NITROGEN-CONTAINING ALICYCLIC SKELETON BONAC CORPORATION (JP) 2012-02-09 US disclosed
US-20120010271-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION BONAC CORPORATION (JP) 2012-01-12 US disclosed
US-20120010271-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION BONAC CORPORATION (JP) 2012-01-12 US disclosed
WO-2011069063-A2 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS, INC. (US) 2011-06-09 WO disclosed
WO-2011069063-A2 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS, INC. (US) 2011-06-09 WO disclosed
EP-1140952-B1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION BIOAGENCY AG (DE) 2003-09-03 EP disclosed
EP-1140952-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION Jomaa Pharmaka GmbH (DE) 2001-10-10 EP disclosed
WO-2000037477-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION JOMAA PHARMAKA GMBH (DE) 2000-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010271-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE FOR CONTROLLING GENE EXPRESSION SRRT, SSU72, RPRD2 L3MBTL1 118/4885POLB 505/4885KMT2A 1767/4885
US-20190125722-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF GRIN2C, NLN, COMT L3MBTL1 3735/4885POLB 2699/4885KMT2A 2379/4885
US-20220387382-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF GRIN2C, NLN, COMT L3MBTL1 3735/4885POLB 2699/4885KMT2A 2379/4885
US-20200323819-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF GRIN2C, NLN, COMT L3MBTL1 3735/4885POLB 2699/4885KMT2A 2379/4885
US-20240358675-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF GRIN2C, NLN, COMT L3MBTL1 3735/4885POLB 2699/4885KMT2A 2379/4885
US-10894033-B2 Multicyclic compounds and methods of use thereof GRIN2C, NLN, COMT L3MBTL1 3735/4885POLB 2699/4885KMT2A 2379/4885
US-10085968-B2 Multicyclic compounds and methods of use thereof GRIN2A, AVPR1A, GRIN2C L3MBTL1 1937/4885POLB 2156/4885KMT2A 859/4885
US-20260034093-A1 MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF SLC6A3, SLC6A11, SLC6A13 L3MBTL1 4557/4885POLB 4657/4885KMT2A 2581/4885
US-20120035246-A1 SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING NITROGEN-CONTAINING ALICYCLIC SKELETON NSUN2, CTDSP1, RNGTT L3MBTL1 188/4885POLB 112/4885KMT2A 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.