Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3524564 | 0.79 | DAO (0.40) | DAO | |
| SCHEMBL28824909 | 0.74 | ALDH1A1 (0.31) | DAO | |
| SCHEMBL16414220 | 0.68 | MEN1 (0.33) | DAO | |
| SCHEMBL5052464 | 0.68 | — | — | |
| SCHEMBL2865050 | 0.65 | MEN1 (0.34) | DAO | |
| SCHEMBL29092664 | 0.62 | — | — | |
| SCHEMBL21811734 | 0.61 | NQO1 (0.35) | — | |
| SCHEMBL28143238 | 0.60 | CYP1A2 (0.44) | DAO | |
| SCHEMBL7779178 | 0.59 | CA5A (0.50) | — | |
| SCHEMBL25139513 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100396667-C | Unsaturated five heterocycle compound for up-regulating bone formation protein BMP-2 expression activity | MEDICINE AND BIOENGINEERING IN (CN) | 2008-06-25 | — | — | CN | disclosed |
| CN-1807411-A | Unsaturated five heterocycle compound for up-regulating bone formation protein BMP-2 expression activity | MEDICINE AND BIOENGINEERING IN (CN) | 2006-07-26 | — | — | CN | disclosed |
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |