Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352579 | 0.88 | CYP1A2 (0.54) | CYP1A2TSHRKDM4EPDE4DALDH1A1 | |
| SCHEMBL4827391 | 0.78 | CYP1A2 (0.48) | CYP1A2TSHRKDM4EPDE4DALDH1A1 | |
| SCHEMBL1311416 | 0.77 | MTOR (0.45) | CYP1A2TSHRKDM4EPDE4DALDH1A1 | |
| SCHEMBL10073316 | 0.76 | PDE4D (0.55) | CYP1A2KDM4EPDE4DALDH1A1HPGD | |
| SCHEMBL15615316 | 0.75 | KMT2A (0.48) | CYP1A2ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL15498679 | 0.75 | PDE4D (0.50) | CYP1A2KDM4EPDE4DALDH1A1HPGD | |
| SCHEMBL19463514 | 0.74 | TDP1 (0.56) | TSHRALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL6855288 | 0.74 | KMT2A (0.54) | CYP1A2PDE4DALDH1A1HPGDHTT | |
| SCHEMBL21174188 | 0.74 | CA12 (0.47) | CYP1A2TSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL9423071 | 0.74 | CYP1A2 (0.55) | CYP1A2SLC2A1KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5186736-A | Pre- and postemergence | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5053072-A | HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |