SCHEMBL6855358

SCHEMBL6855358

C[C]1C(=O)C=C(C)C(=O)C1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 1/20 0.33
PLK1 P53350 1/20 0.33
PLK2 Q9NYY3 1/20 0.33
MEN1 O00255 2/20 0.32
USP2 O75604 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
BLM P54132 2/20 0.32
KMT2A Q03164 2/20 0.32
PLIN1 O60240 1/20 0.32
NR1I2 O75469 1/20 0.32
GSR P00390 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31679699 0.74
P-Xyloquinone SCHEMBL49964 0.65 PLK1 (0.60) EEF2KPLK1PLK2MEN1USP2
SCHEMBL3624714 0.65 ALDH1A1 (0.50) EEF2KPLK1PLK2MEN1USP2
SCHEMBL22466 0.62
SCHEMBL14810133 0.60
SCHEMBL4956590 0.60
SCHEMBL11124632 0.60
SCHEMBL10351240 0.60
SCHEMBL9744771 0.57
SCHEMBL6205673 0.56 MEN1 (0.38) EEF2KPLK1PLK2MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US claimed
US-4959362-A FREE RADICAL SCAVENGERS TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1990-09-25 US claimed
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US disclosed