Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862543 | 0.80 | GPR35 (0.40) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL29062045 | 0.79 | GPR35 (0.41) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL5282461 | 0.79 | GPR35 (0.41) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL3447197 | 0.78 | GPR35 (0.46) | GPR35TP53CYP3A4ALOX5KCNH2 | |
| SCHEMBL6154380 | 0.72 | LIPG (0.40) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL28876813 | 0.72 | GPR35 (0.40) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL13429481 | 0.70 | GPR35 (0.44) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL2279352 | 0.70 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL27825706 | 0.70 | GPR35 (0.44) | GPR35CYSLTR2CYSLTR1LIPGTYR | |
| SCHEMBL1156926 | 0.70 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1LIPGTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6676857-B2 | FOR USE AS SEMICONDUCTORS OR CHARGE TRANSPORT MATERIALS IN OPTICAL, ELECTROOPTICAL OR ELECTRONIC DEVICES INCLUDING FIELD EFFECT TRANSISTORS, ELECTROLUMINESCENT, PHOTOVOLTAIC AND SENSOR DEVICES | MERCK PATENT GESELLSCHAFT MIT (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20030047720-A1 | Mono-, oligo- and poly-4- fluorothiophenes and their use as charge transport materials | MERCK PATENT GMBH (DE) | 2003-03-13 | — | — | US | disclosed |
| EP-1279690-A1 | Mono-oligo- and poly-3-substituted-4-fluorothiophenes and their use as charge transport materials | MERCK PATENT GmbH (DE) | 2003-01-29 | — | — | EP | disclosed |