Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850058 | 0.84 | MALT1 (0.39) | RXFP1MALT1ALDH1A1MAPTPARP10 | |
| SCHEMBL6854060 | 0.69 | NPC1 (0.39) | MALT1HPGD | |
| SCHEMBL16621634 | 0.56 | CYP2A6 (0.40) | RXFP1SMN1; SMN2ALDH1A1MAPTPARP10 | |
| SCHEMBL15345098 | 0.56 | KDR (0.38) | RXFP1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL24576002 | 0.54 | ALDH1A1 (0.53) | RXFP1SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL17265046 | 0.54 | MAPT (0.47) | RXFP1SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL25880201 | 0.54 | KDM4E (0.37) | RXFP1SMN1; SMN2ALDH1A1MAPTPARP10 | |
| SCHEMBL15345117 | 0.53 | ADORA2A (0.41) | ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL31414199 | 0.53 | KMT2A (0.66) | RXFP1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL793546 | 0.53 | BCHE (0.56) | RXFP1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |