SCHEMBL25880201

SCHEMBL25880201

Cc1ccc2c(c1)c1cc(C)cc3c1n2c1cc(C)cc2c4cc(C)ccc4n3c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
RAB9A P51151 2/20 0.37
APAF1 O14727 1/20 0.37
PKM P14618 1/20 0.37
IDO1 P14902 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
MCL1 Q07820 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP1A2 P05177 4/20 0.37
CYP2A6 P11509 4/20 0.37
RXFP1 Q9HBX9 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34
AHR P35869 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880197 0.94 KDM4E (0.38) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL16621634 0.91 CYP2A6 (0.40) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL25880198 0.88 CYP1A2 (0.37) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL25880215 0.87 ALKBH5 (0.40) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL26179671 0.84 PGR (0.45) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL17265054 0.82 BCHE (0.42) KDM4EMAPTTDP1MAPK1HTT
SCHEMBL25634963 0.82 BCHE (0.42) KDM4EMAPTTDP1MAPK1HTT
SCHEMBL26179694 0.82 PGR (0.41) KDM4EMAPTTDP1RAB9AAPAF1
SCHEMBL25880167 0.82 GPR3 (0.41) KDM4EMAPTHTTCYP1A2CYP2A6
SCHEMBL25635416 0.81 PGR (0.43) KDM4EMAPTTDP1RAB9AAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 KDM4E 1533/4885MAPT 4078/4885TDP1 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.