SCHEMBL6855769

SCHEMBL6855769

CCCCCCCCCCN([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.50
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GBA1 P04062 1/20 0.37
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22116238 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL22116235 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL6859258 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL6857828 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL3873514 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL23778608 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL6851065 1.00 DNM1 (0.50) DNM1TSHRTHRBCA12CA1
SCHEMBL6857846 0.97 DNM1 (0.46) DNM1TSHRTHRBCA12CA1
SCHEMBL6857940 0.88 TSHR (0.35) DNM1TSHRTHRBCA12CA1
SCHEMBL3692723 0.80 DNM1 (0.33) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3873953-B1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-10-16 EP disclosed
US-11952440-B2 Process for the preparation of polyethylenes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-04-09 US disclosed
US-20210371553-A1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-02 US disclosed
EP-3873953-A1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC Global Technologies B.V. (NL) 2021-09-08 EP disclosed
US-6737193-B2 ACTIVE MATERIALS IN THE POSITIVE ELECTRODES OF BATTERIES. NOVEL METHODS FOR PREPARING THE TETRAKETOPIPERAZINE UNIT-CONTAINING COMPOUNDS INCLUDE: (I) REACTING AN OXALYL HALIDE AND AN OXAMIDE, AND ADDING WATER OR AN AQUEOUS ALKALI IM&T RESEARCH, INC. 2004-05-18 US disclosed
US-20030148188-A1 Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali IM&T RESEARCH, INC. 2003-08-07 US disclosed