Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858194 | 0.83 | ADORA2A (0.43) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL9382837 | 0.76 | CRBN (0.44) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL3321300 | 0.70 | ALDH1A1 (0.52) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL5720522 | 0.69 | ADORA2A (0.46) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL30731231 | 0.69 | ADORA2A (0.46) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL24569651 | 0.69 | ADORA2A (0.46) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL4627301 | 0.69 | ADORA2A (0.46) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL14935698 | 0.68 | ADORA2A (0.58) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL14935697 | 0.68 | ADORA2A (0.58) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 | |
| SCHEMBL29682688 | 0.66 | PARP1 (0.44) | ADORA2AALDH1A1RAB9AHTTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |