SCHEMBL6856091

SCHEMBL6856091

CCCCCCCCCCCCCCCCCCOC(C=O)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.45
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 3/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 2/20 0.43
BLM P54132 2/20 0.43
ATM Q13315 2/20 0.43
HIF1A Q16665 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
USP2 O75604 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
GAA P10253 3/20 0.37
NR1I2 O75469 1/20 0.37
CNR1 P21554 3/20 0.36
CNR2 P34972 2/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194402 0.83 HMGCR (0.33) HMGCRKMT2AALDH1A1TSHRMEN1
SCHEMBL10697139 0.83 THRA (0.32) HMGCRCNR1CNR2THRATHRB
SCHEMBL1695375 0.80 HMGCR (0.31) HMGCR
SCHEMBL11616289 0.77 HMGCR (0.43) HMGCRKMT2AALDH1A1TSHRMEN1
SCHEMBL5405788 0.77 HMGCR (0.47) HMGCRKMT2AGAA
SCHEMBL9431158 0.76 HMGCR (0.46) HMGCRKMT2AGAA
SCHEMBL9431242 0.76 HMGCR (0.46) HMGCRKMT2AGAA
SCHEMBL581163 0.75 HMGCR (0.45) HMGCRKMT2AATMNPSR1GAA
SCHEMBL10433646 0.75 HMGCR (0.45) HMGCRKMT2AATMNPSR1GAA
SCHEMBL3350955 0.75 HMGCR (0.45) HMGCRKMT2AATMNPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2569356-B1 POLYMER COMPOSITION HAVING HEAT-ABSORBENT PROPERTIES AND HIGH STABILITY BAYER IP GMBH (DE) 2014-12-17 EP claimed
US-12163640-B2 Three part headlamp assembly COVESTRO LLC 2024-12-10 US disclosed
US-20240280239-A1 THREE PART HEADLAMP ASSEMBLY COVESTRO LLC 2024-08-22 US disclosed
US-12007093-B2 Three part headlamp assembly COVESTRO LLC (US) 2024-06-11 US disclosed
US-20220397258-A1 THREE PART HEADLAMP ASSEMBLY COVESTRO LLC 2022-12-15 US disclosed
EP-3592525-B1 TWO SHOT INJECTION MOLDING PROCESS FOR THERMOPLASTIC PARTS COVESTRO LLC (US) 2022-04-13 EP disclosed
WO-2018164666-A1 TWO SHOT INJECTION MOLDING PROCESS FOR THERMOPLASTIC PARTS COVESTRO LLC (US) 2018-09-13 WO disclosed
US-20140356551-A1 MOLDED BODIES HAVING HIGH SURFACE QUALITY COVESTRO DEUTSCHLAND AG (DE) 2014-12-04 US disclosed
US-8455581-B2 Antistatic polycarbonate moulding compositions BAYER MATERIALSCIENCE AG (DE) 2013-06-04 US disclosed
US-20120165442-A1 ANTISTATIC POLYCARBONATE MOULDING COMPOSITIONS BAYER MATERIALSCIENCE AG (DE) 2012-06-28 US disclosed
US-6783160-B2 Plastic-lined metal-encased tubing segment connector system MERCURY PLASTICS, INC. 2004-08-31 US disclosed
EP-0280938-A1 Antioxidant aromatic fluorophosphites ALBEMARLE CORPORATION (US) 1988-09-07 EP disclosed