SCHEMBL194402

SCHEMBL194402

CCCCCCCCOC(C=O)Cc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.33
F2R P25116 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
POLB P06746 1/20 0.32
CNR2 P34972 1/20 0.31
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27963576 0.91 CNR2 (0.33) F2RNPC1RAB9APOLBCNR2
SCHEMBL1695375 0.91 HMGCR (0.31) HMGCR
SCHEMBL8050308 0.89 PTGS2 (0.33)
SCHEMBL295015 0.86 CA2 (0.34) HMGCRNPC1RAB9APOLBALDH1A1
SCHEMBL139808 0.85 NPC1 (0.37) HMGCRF2RNPC1RAB9APOLB
SCHEMBL6856091 0.83 HMGCR (0.45) HMGCRCNR2THRATHRBMEN1
SCHEMBL18517336 0.81 CNR2 (0.33) F2RNPC1RAB9APOLBCNR2
SCHEMBL7701744 0.80 CNR2 (0.38) F2RNPC1RAB9APOLBCNR2
SCHEMBL20614156 0.80 NPC1 (0.36) HMGCRF2RNPC1RAB9APOLB
SCHEMBL547105 0.79 PTGES (0.41) F2RNPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916867-B2 Synergistic mixtures of UV-absorbers in polyolefins CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-07-12 US claimed
EP-2978805-B1 STABILIZER COMPOSITIONS COMPRISING SALTS OF DICARBOXYLIC ACIDS AND POLYOLS BAERLOCHER GMBH (DE) 2023-11-15 EP disclosed
US-20220235215-A1 AQUEOUS DISPERSION AND AQUEOUS COATING COMPOSITION COMPRISING THE SAME DOW SILICONES CORPORATION 2022-07-28 US disclosed
US-10793555-B2 Oxime ester photoinitiators BASF SE (DE) 2020-10-06 US disclosed
US-20180208583-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-26 US disclosed
EP-3027694-A1 AQUEOUS COATING COMPOSITION WITH IMPROVED DURABILITY Dow Global Technologies LLC (US) 2016-06-08 EP disclosed
EP-2993168-A1 PROCESS FOR THE SYNTHESIS OF N-ALKOXYAMINES BASF SE (DE) 2016-03-09 EP disclosed
EP-2978805-A1 STABILIZER COMPOSITIONS COMPRISING SALTS OF DICARBOXYLIC ACIDS AND POLYOLS Baerlocher GmbH (DE) 2016-02-03 EP disclosed
EP-1769286-B1 OXIME DERIVATIVES AND THE USE THEROF AS LATENT ACIDS BASF SE (DE) 2015-09-09 EP disclosed
US-8993660-B2 Antistatic thermoplastic compositions BASF SE (DE) 2015-03-31 US disclosed
WO-1998054177-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed
WO-1998054174-A1 BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-12-03 WO disclosed
EP-0880557-A1 STABILISATION OF POLYOLEFIN-RECYCLATES Ciba SC Holding AG (CH) 1998-12-02 EP disclosed
EP-0880553-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES Ciba SC Holding AG (CH) 1998-12-02 EP disclosed
WO-1998028361-A1 LIGHT-STABILISED FLAMEPROOF STYRENE HOMOPOLYMERS AND COPOLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-02 WO disclosed
WO-1998003489-A1 POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-29 WO disclosed
WO-1997030105-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-08-21 WO disclosed
WO-1997030112-A1 STABILISATION OF POLYOLEFIN-RECYCLATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-08-21 WO disclosed
EP-0718357-A2 Flame-resistant moulding composition having improved light stability HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-26 EP disclosed
EP-0690060-A1 Two crystal modifications of a diketopyrrolopyrrole HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793555-B2 Oxime ester photoinitiators NR2E3, OXER1, CBR3 HMGCR 1321/4885F2R 3333/4885NPC1 3823/4885
US-20180208583-A1 OXIME ESTER PHOTOINITIATORS NR2E3, OXER1, CBR3 HMGCR 1321/4885F2R 3333/4885NPC1 3823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.