Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320487 | 0.82 | AKR1C3 (0.54) | MEN1KMT2AAKR1C3MRGPRX4NR4A2 | |
| SCHEMBL475754 | 0.82 | AURKA (0.56) | AURKATPX2WDR5ALDH1A1HSD17B10 | |
| SCHEMBL9171619 | 0.81 | TSHR (0.57) | AURKATPX2ALDH1A1HSD17B10TSHR | |
| SCHEMBL6854223 | 0.80 | NOTUM (0.49) | ALDH1A1HSD17B10TSHRCA12CA1 | |
| SCHEMBL31550001 | 0.78 | AURKA (0.56) | AURKATPX2WDR5ALDH1A1HSD17B10 | |
| SCHEMBL29482059 | 0.74 | WDR5 (0.51) | AURKATPX2WDR5TTRCA1 | |
| SCHEMBL1871974 | 0.74 | WDR5 (0.51) | AURKATPX2WDR5TTRCA1 | |
| SCHEMBL1439934 | 0.74 | AURKA (0.34) | AURKATPX2WDR5ALDH1A1HSD17B10 | |
| SCHEMBL12285644 | 0.74 | TPMT (0.43) | ALDH1A1HSD17B10MEN1KMT2ACA12 | |
| SCHEMBL24017256 | 0.73 | TPMT (0.48) | AURKATPX2ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095071-B1 | AROMATIC POLYMERS WITH PENDANT FLUORINATED IONIC GROUPS | DU PONT (US) | 2004-06-16 | — | — | EP | disclosed |