SCHEMBL6856192

SCHEMBL6856192

CC(C)NC(=O)Cc1cc2cc(N3CC(CN4CCOCC4)C3)ccc2nc1-c1ccc(F)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AVPR1B P47901 17/20 0.46
AVPR1A P37288 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857461 0.83 AVPR1B (0.44) AVPR1BAVPR1A
SCHEMBL6857013 0.81 AVPR1B (0.42) AVPR1B
SCHEMBL6856269 0.81 AVPR1B (0.40) AVPR1B
SCHEMBL6857248 0.81 AVPR1B (0.55) AVPR1B
SCHEMBL6856988 0.81 AVPR1B (0.53) AVPR1B
SCHEMBL6856002 0.80 SOS1 (0.39) AVPR1B
SCHEMBL6857414 0.80 AVPR1B (0.38) AVPR1B
SCHEMBL6857457 0.80 HRH1 (0.43)
SCHEMBL6857094 0.80 ENPP2 (0.41) AVPR1B
SCHEMBL6857187 0.77 AVPR1B (0.49) AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011096461-A1 QUINOLINE DERIVATIVE 大正製薬株式会社 (JP) 2011-08-11 WO disclosed