Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525607 | 0.78 | HSD17B10 (0.62) | HSD17B10DAOGRM5L3MBTL1MEN1 | |
| SCHEMBL1382465 | 0.75 | HSD17B10 (0.57) | HSD17B10DAOGRM5L3MBTL1MEN1 | |
| SCHEMBL5865442 | 0.75 | HSD17B10 (0.57) | HSD17B10DAOGRM5L3MBTL1MEN1 | |
| SCHEMBL3281437 | 0.74 | HSD17B10 (1.00) | HSD17B10DAOGRM5MEN1ALDH1A1 | |
| SCHEMBL17525771 | 0.73 | HSD17B10 (0.51) | HSD17B10DAOGRM5L3MBTL1MEN1 | |
| SCHEMBL10159126 | 0.72 | MAPT (0.61) | HSD17B10GRM5L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL41923 | 0.70 | ALDH1A1 (0.64) | HSD17B10L3MBTL1MEN1ALDH1A1PKM | |
| SCHEMBL6809288 | 0.70 | ATAD2 (0.55) | HSD17B10GRM5ACHEHRH1 | |
| SCHEMBL2135730 | 0.70 | HSD17B10 (0.51) | HSD17B10DAOL3MBTL1MEN1KMT2A | |
| SCHEMBL6856114 | 0.70 | HSD17B10 (0.51) | HSD17B10DAOL3MBTL1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |